Module1.png
Introduction & Databases
Module2.png
BLAST
Module3.png
Alignments & Trees
Module4.png
Protein structure & modeling
Module5.png
Predictions
Module6.png
Pathways & Interactions
testweek.png
Test week
Fireworks Show
Project Launch

For module 1:

Watch Where do sequences come from? (16 min) in the video player below. You also have access to the slides below.

Review activities and slides from Day 1.

Start studying the material for the amino acids and for Module 2. 

For module 2:

Watch 2 lectures Sequence similarity (24  min) and BLAST (18 min) below.

Check out the 4 buttons on the right >>>

Review activities and slides from Week 1.

Since there is no class on Monday, use the study guide to prepare for class on Wednesday and for Quiz 1-2.

Jan 11 - Jan 13

Jan 20

Jan 25 - Jan 27

Feb 1 - Feb 3

Feb 8 - Feb 10

Feb 15 - Feb 17

For module 3:

Before class on Monday: 

Watch the lecture on Multiple Sequence Alignments (13 min) below.

Before class on Wednesday:

Watch the two lectures on Phylogenetics (20 and 14 min each) below.

Review activities and slides from Weeks 1-2.

For module 4:

Before class on Monday: 

Watch the in the following order:

1. What is a protein?

2. the lecture on Protein Structure & Domains

3. The 2017 Nobelprize in Chemistry: Cryo EM

(all are found below)

Before class on Wednesday:

Review all activities, slides, videos for the quiz.

For module 5:

Before class on Monday: 

Watch the in the following order:

1. What is a protein?

2. the lecture on Protein Structure & Domains

3. The 2017 Nobelprize in Chemistry: Cryo EM

Before class on Wednesday:

Review all activities, slides, videos for the quiz.

Have you seen the NEWS? AlphaFold | DeepMind 

‘It will change everything’: DeepMind’s AI makes gigantic leap in solving protein structures (nature.com)

Zoom recordings are posted with the other videos below.

For module 6:

Before class on Monday: 

Complete the part of the PFAM course from beginning to "Getting data from PFAM" found here: Pfam | Training Content Hub (ebi.ac.uk) 

Before class on Wednesday:

Review all materials!.  Start studying for the tests next week. 

For the tests:

Review materials and activities

Complete study guides

Quizzes are showing your answers and the correct answer

New review videos recordings from last class are posted below

Additional study guide question:

When a blast search is performed, the results are by default sorted by E-value. What does the E-value reflect?  What does the E-value depend upon?                                                                                          

whatisaprotein.png
Cryo-EM.PNG